TY - GEN T1 - Real-life experience with high-frequency chest wall oscillation vest therapy in adults with non-cystic fibrosis bronchiectasis AU - Barto, Tara Lynn AU - Maselli, Diego Jose AU - Daignault, Sarah AU - Stiglich, John AU - Porter, Jared AU - Carlye Kraemer AU - Hansen, Gary DO - 10.25384/SAGE.C.5023286 UR - https://sage.figshare.com/collections/Real-life_experience_with_high-frequency_chest_wall_oscillation_vest_therapy_in_adults_with_non-cystic_fibrosis_bronchiectasis/5023286 AB - Background:High frequency chest wall oscillation (HFCWO) has long been used for airway clearance for patients with cystic fibrosis. Only limited research has evaluated this therapy in adult patients with non-cystic fibrosis bronchiectasis (NCFB).Methods:Data from 2596 patients from a registry of adult bronchiectasis patients using HFCWO therapy was used to evaluate hospitalization patterns before and after initiation of HFCWO therapy, as well as antibiotic use and self-reported metrics of quality of life. Self-reported outcomes were also reviewed by cross-checking with sampled patient charts and found to be consistent.Results:The number of patients who had at least one respiratory-related hospitalization decreased from 49.1% (192/391) in the year before to 24.0% (94/391) in the year after starting HFCWO therapy (p-value p p p Conclusion:NCFB patients showed improved self-reported outcomes associated with the initiation of HFCWO therapy as measured by number of hospitalizations, antibiotic use, and the subjective experience of airway clearance. The improvement was observed early on after initiation of therapy and sustained for at least 1 year.The reviews of this paper are available via the supplemental material section. KW - 111702 Aged Health Care KW - FOS: Health sciences KW - 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified KW - FOS: Clinical medicine KW - 110203 Respiratory Diseases PY - 2020 PB - SAGE Journals ER -